Validation of Scoring Systems for Predicting Severe Community-Acquired Pneumonia

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Severe community-acquired pneumonia.

Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. It accounts for 500,000 hospitalizations and 45,000 deaths each year, and it represents one of the most common causes of ICU admission. The mortality rate due to severe CAP has shown little improvement over the past few years, with rates as high as 58% when patients were admitted to t...

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Corticosteroid treatment of severe community-acquired pneumonia.

OBJECTIVE To assess the evidence for adjunctive corticosteroids for severe community-acquired pneumonia (CAP). DATA SOURCES MEDLINE (1966-February 2007) and EMBASE (1980-February 2007) were searched to identify English- and French-language publications that evaluated the use of corticosteroids for CAP in adults. Major search terms included community-acquired pneumonia, intensive care unit, st...

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Middle molecules in severe community-acquired pneumonia

Results Patients admitted had mean age of 62 ± 1.2 years, PORT classes IV-V and mean Pneumonia Severity Index score of 108.5 ± 3.8. In all patients on admission there was a high level of endogenous intoxication manifested by 1.8 times increasing levels of MM compared to the control group (0.262 ± 0.001 versus 0.146 ± 0.02 optic units, p < 0.05). There was a positive trend with a decline of MM o...

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[Severe community-acquired pneumonia in adults].

Patients with severe community acquired pneumonia (CAP) need continuous surveillance and monitoring at intensive care units (ICU), where they can receive specialized support as mechanical ventilation and/or hemodynamic support. Patients that require ICU admittance represent 10 to 30% of all patients interned because a pneumonia. In this category, high complication rate, prolonged hospital stay ...

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Novel biomarkers in severe community-acquired pneumonia.

Community-acquired pneumonia (CAP) is the most common infectious disease requiring admission to intensive care units (ICUs), and achieving an early and precise diagnosis of CAP remains a challenge. Biomarkers play an important role in improving clinical judgment in the emergency room and are adjuvant in evaluating treatment responses. Novel biomarkers, such as cortisol, pro-adrenomedullin and e...

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2011

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.50.5279